MP20:Price:Robots:Rapid On-Bead Oligomer-Target Screening
From LabAutopedia
Alexander K. Price and Brian M. Paegel
The Scripps Research Institute, Jupiter FL 33458
Identification of functional probes for the entire human proteome using conventional microplate-based high-throughput screening (HTS) is a daunting challenge that will take decades and cost billions of dollars. Since its inception, the Molecular Libraries Program (MLP) has discovered ~200 probes at a cost of roughly $2 million per probe. To put this in perspective, it is estimated that probing the entire human proteome will require ~50-100k selective molecules. We are engineering miniaturized "next-generation" systems that will accelerate the pace of discovery and decrease the cost by screening one-bead-one-compound (OBOC) libraries at > 50k molecules per hour.
| Click [+] for other articles on |
| The Market Place for Lab Automation & Screening | The Market Place |
